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Converging cellular themes for the hereditary spastic paraplegias
Hereditary spastic paraplegias (HSPs) are neurologic disorders characterized by prominent lower-extremity spasticity, resulting from a length-dependent axonopathy of corticospinal upper motor neurons. They are among the most genetically-diverse neurologic disorders, with >80 distinct genetic loci...
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| Publicat a: | Curr Opin Neurobiol |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066444/ https://ncbi.nlm.nih.gov/pubmed/29753924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conb.2018.04.025 |
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