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An RNA-Binding Multimer Specifies Nematode Sperm Fate
FOG-3 is a master regulator of sperm fate in Caenorhabditis elegans and homologous to Tob/BTG proteins, which in mammals are monomeric adaptors that recruit enzymes to RNA binding proteins. Here, we determine the FOG-3 crystal structure and in vitro demonstrate that FOG-3 forms dimers that can multi...
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| Udgivet i: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066285/ https://ncbi.nlm.nih.gov/pubmed/29949762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.095 |
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