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Photo-Immobilized EGF Chemical Gradients Differentially Impact Breast Cancer Cell Invasion and Drug Response in Defined 3D Hydrogels

Breast cancer cell invasion is influenced by growth factor concentration gradients in the tumor microenvironment. However, studying the influence of growth factor gradients on breast cancer cell invasion is challenging due to both the complexities of in vivo models and the difficulties in recapitula...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Fisher’, Stephanie A., Tam, Roger Y., Fokina, Ana, Mahmoodi, M. Mohsen, Distefano, Mark D., Shoichet, Molly S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066187/
https://ncbi.nlm.nih.gov/pubmed/29452913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.01.032
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