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Mechanistic effect of the human GJB6 gene and its mutations in HaCaT cell proliferation and apoptosis
We constructed lentiviral vectors containing the human wild-type GJB6 gene and the mutant variants A88V and G11R. The three proteins were stably expressed by the Tet-on system in the HaCaT cell line and used to study the functional effect of the variants. The CCK-8 assay and flow cytometric analyses...
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| Опубликовано в: : | Braz J Med Biol Res |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Associação Brasileira de Divulgação Científica
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065815/ https://ncbi.nlm.nih.gov/pubmed/30043857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20187560 |
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