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Fc-apelin fusion protein attenuates lipopolysaccharide-induced liver injury in mice

Apelin is a peptide hormone with anti-oxidative and anti-inflammatory activities and is proposed to be a potential therapeutic for many disease conditions, including sepsis. However, short in vivo half-life of the apelin peptide would limit its potential clinical applications. This study aims to inv...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Huifen, Yang, Rongze, Wang, Weimin, Xu, Feng, Xi, Yue, Brown, Robert A., Zhang, Hong, Shi, Lin, Zhu, Dalong, Gong, Da-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065397/
https://ncbi.nlm.nih.gov/pubmed/30061611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29491-7
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