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Glibenclamide Enhances the Therapeutic Benefits of Early Hypothermia after Severe Stroke in Rats

Glibenclamide (GBC) is an antidiabetic drug that is in a class of medications known as sulfonylureas, which play critical roles in attenuating brain edema and reducing mortality in ischemic stroke patients. Therapeutic hypothermia (TH) is another robust neuroprotectant that prevents brain swelling a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging Dis
Hauptverfasser: Zhu, Shuzhen, Gao, Xiaoya, Huang, Kaibin, Gu, Yong, Hu, Yafang, Wu, Yongming, Ji, Zhong, Wang, Qing, Pan, Suyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: JKL International LLC 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065285/
https://ncbi.nlm.nih.gov/pubmed/30090656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.0927
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