Aberrant Protein Turn-Over Associated With Myofibrillar Disorganization in FHL1 Knockout Mice

Mutations in the FHL1 gene, and FHL1 protein deletion, are associated with rare hereditary myopathies and cardiomyopathies. FHL1-null mice develop age-dependent myopathy and increased autophagic activity. However, the molecular pathway involved in contractile function and increased autophagic activi...

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Bibliographic Details
Published in:Front Genet
Main Authors: Ding, Jingjing, Cong, Yan Fei, Liu, Bo, Miao, Jianing, Wang, Lili
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065255/
https://ncbi.nlm.nih.gov/pubmed/30083183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00273
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