Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

BACKGROUND: Gastrointestinal stromal tumour (GIST) is the most common soft tissue sarcoma. The identification of the molecular mechanisms regulating GIST progression is vital for its treatment and prevention. Increasing reports have demonstrated that epigenetic alterations play critical roles in GIS...

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Foilsithe in:Mol Cancer
Main Authors: Hu, Fuqing, Li, Haijie, Liu, Lu, Xu, Feng, Lai, Senyan, Luo, Xuelai, Hu, Junbo, Yang, Xi
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065154/
https://ncbi.nlm.nih.gov/pubmed/30060750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0861-6
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