C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune neuroinflammatory disease. In contrast to multiple sclerosis, autoantibodies against aquaporin-4 (AQP4) expressed on astrocytic end-feet have been exclusively detected in sera of NMOSD patients. Several lines of evidence suggested that...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Piatek, Paweł, Domowicz, Małgorzata, Lewkowicz, Natalia, Przygodzka, Patrycja, Matysiak, Mariola, Dzitko, Katarzyna, Lewkowicz, Przemysław
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065055/
https://ncbi.nlm.nih.gov/pubmed/30083159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01694
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