Gastrin Protects Against Myocardial Ischemia/Reperfusion Injury via Activation of RISK (Reperfusion Injury Salvage Kinase) and SAFE (Survivor Activating Factor Enhancement) Pathways

BACKGROUND: Ischemia/reperfusion injury (IRI) is one of the most predominant complications of ischemic heart disease. Gastrin has emerged as a regulator of cardiovascular function, playing a key protective role in hypoxia. Serum gastrin levels are increased in patients with myocardial infarction, bu...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Yang, Xiaoli, Yue, Rongchuan, Zhang, Jun, Zhang, Xiaoqun, Liu, Yukai, Chen, Caiyu, Wang, Xinquan, Luo, Hao, Wang, Wei Eric, Chen, Xiongwen, Wang, Huixia Judy, Jose, Pedro A., Wang, Hongyong, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064830/
https://ncbi.nlm.nih.gov/pubmed/30005556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005171
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