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Sphingosine 1 phosphate receptor-1 (S1PR1) signaling protects cardiac function by inhibiting cardiomyocyte autophagy
OBJECTIVE: To investigate the role of sphingosine-1-phosphate (S1P) and its receptors in cardiomyocyte autophagy, cardiomyocyte hypertrophy and cardiac function. METHODS: Cardiomyocytes were isolated from neonatal Vista rats. Autophagy and hypertrophy of cardiomyocytes were induced via starvation cu...
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| Publicado no: | J Geriatr Cardiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Science Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6064777/ https://ncbi.nlm.nih.gov/pubmed/30083186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11909/j.issn.1671-5411.2018.05.003 |
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