Construction of Lactobacillus casei ghosts by Holin-mediated inactivation and the potential as a safe and effective vehicle for the delivery of DNA vaccines

BACKGROUND: Bacterial ghosts (BGs) are empty bacterial cell envelopes generated by releasing the cellular contents. In this study, a phage infecting Lactobacillus casei ATCC 393 (L. casei 393) was isolated and designated Lcb. We aimed at using L. casei 393 as an antigen delivery system to express ph...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Hou, Rui, Li, Muzi, Tang, Tingting, Wang, Ruichong, Li, Yijing, Xu, Yigang, Tang, Lijie, Wang, Li, Liu, Min, Jiang, Yanping, Cui, Wen, Qiao, Xinyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064150/
https://ncbi.nlm.nih.gov/pubmed/30055567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-018-1216-6
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