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Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress

Upregulation of histone acetylation plays a critical role in the dysregulation of transcription. It alters the structure of chromatin, which leads to the onset of cancer. Histone deacetylase inhibitors may therefore be a promising way to limit cancer progression. In this study, we examined the effec...

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Библиографические подробности
Опубликовано в: :Cell Mol Biol Lett
Главные авторы: Huang, Ying, Yang, Wuping, Zeng, Huihong, Hu, Chuan, Zhang, Yaqiong, Ding, Nanhua, Fan, Guangqin, Shao, Lijian, Kuang, Bohai
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064062/
https://ncbi.nlm.nih.gov/pubmed/30065760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-018-0101-5
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