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Effect of Thrombin-Induced MCP-1 and MMP-3 Production Via PAR1 Expression in Murine Intervertebral Discs

Structural changes in nucleus pulposus cells induce intervertebral disc (IVD) degeneration as a consequence of cytokine generation, biochemical products, and changes in the local environment. We have previously shown that inflammatory cytokines induce murine IVD (mIVD) angiogenesis and macrophage mi...

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發表在:Sci Rep
Main Authors: Takayama, Yoshihiro, Ando, Takashi, Ichikawa, Jiro, Haro, Hirotaka
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063965/
https://ncbi.nlm.nih.gov/pubmed/30054581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29669-z
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