Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin

Although previous studies have indicated important roles of palmitate, a saturated fatty acid, in the pathogenesis of nonalcoholic fatty liver disease (NAFLD), it remains unclear how palmitate contributes to inflammation and fibrosis in the liver. Administration of palmitate in high fat diet (HFD)-f...

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Publicado no:Sci Rep
Main Authors: Ogawa, Yuji, Imajo, Kento, Honda, Yasushi, Kessoku, Takaomi, Tomeno, Wataru, Kato, Shingo, Fujita, Koji, Yoneda, Masato, Saito, Satoru, Saigusa, Yusuke, Hyogo, Hideyuki, Sumida, Yoshio, Itoh, Yoshito, Eguchi, Kosei, Yamanaka, Takeharu, Wada, Koichiro, Nakajima, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063851/
https://ncbi.nlm.nih.gov/pubmed/30054551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29735-6
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