Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin

Although previous studies have indicated important roles of palmitate, a saturated fatty acid, in the pathogenesis of nonalcoholic fatty liver disease (NAFLD), it remains unclear how palmitate contributes to inflammation and fibrosis in the liver. Administration of palmitate in high fat diet (HFD)-f...

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Publicado en:Sci Rep
Main Authors: Ogawa, Yuji, Imajo, Kento, Honda, Yasushi, Kessoku, Takaomi, Tomeno, Wataru, Kato, Shingo, Fujita, Koji, Yoneda, Masato, Saito, Satoru, Saigusa, Yusuke, Hyogo, Hideyuki, Sumida, Yoshio, Itoh, Yoshito, Eguchi, Kosei, Yamanaka, Takeharu, Wada, Koichiro, Nakajima, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063851/
https://ncbi.nlm.nih.gov/pubmed/30054551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29735-6
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