Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis

BACKGROUND: Despite increasing ethical standards for conducting animal research, death is still often used as an endpoint in mouse sepsis studies. Recently, the Murine Sepsis Score (MSS), Mouse Clinical Assessment Score for Sepsis (M-CASS), and Mouse Grimace Scale (MGS) were developed as surrogate e...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Mai, Safiah H. C., Sharma, Neha, Kwong, Andrew C., Dwivedi, Dhruva J., Khan, Momina, Grin, Peter M., Fox-Robichaud, Alison E., Liaw, Patricia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063809/
https://ncbi.nlm.nih.gov/pubmed/30054760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-018-0184-3
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