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Simple kinetic model of mitochondrial swelling in cardiac cells

Mitochondria play an important role in both cell survival and cell death. In response to oxidative stress, they undergo opening of non-selective permeability transition pores (PTP) in the inner mitochondrial membrane. Sustained PTP opening triggers mitochondrial swelling due to increased colloidal o...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: Chapa-Dubocq, Xavier, Makarov, Vladimir, Javadov, Sabzali
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063534/
https://ncbi.nlm.nih.gov/pubmed/29215716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26335
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