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Fibrin films: overlooked hemostatic barriers against microbial infiltration

The hemostatic response to vascular injury culminates in a fibrin clot network that forms an initial barrier to blood loss and also contributes to microbial host defense. Fibrinogen is cleaved by thrombin into fibrin monomers that spontaneously polymerize into protofibrils and form the extensive fib...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gu, Sean X., Lentz, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063499/
https://ncbi.nlm.nih.gov/pubmed/29939163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121858
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