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Physiological responses to leptin levels in lipodystrophy: a model for other hypoleptinemias?

Brown et al. report that two weeks of exogenous leptin administration to leptin-naive individuals with lipodystrophy resulted in increased energy expenditure and lipolysis, decreased ectopic liver fat, improved hepatic and peripheral insulin sensitivity, and attenuated dyslipidemia. Leptin withdrawa...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rosenbaum, Michael, Leibel, Rudolph L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063491/
https://ncbi.nlm.nih.gov/pubmed/30010621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122042
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