Optimal bone fracture repair requires 24R,25-dihydroxyvitamin D(3) and its effector molecule FAM57B2

The biological activity of 24R,25-dihydroxyvitamin D(3) [24R,25(OH)(2)D(3)] remains controversial, but it has been suggested that it contributes to fracture healing. Cyp24a1(–/–) mice, synthesizing no 24R,25(OH)(2)D(3), show suboptimal endochondral ossification during fracture repair, with smaller c...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Martineau, Corine, Naja, Roy Pascal, Husseini, Abdallah, Hamade, Bachar, Kaufmann, Martin, Akhouayri, Omar, Arabian, Alice, Jones, Glenville, St-Arnaud, René
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063485/
https://ncbi.nlm.nih.gov/pubmed/30010626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98093
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