Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

Chemical pollutant exposure is a risk factor contributing to the growing epidemic of non-alcoholic fatty liver disease (NAFLD) affecting human populations that consume a western diet. Although it is recognized that intoxication by chemical pollutants can lead to NAFLD, there is limited information a...

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Publicat a:Arch Toxicol
Autors principals: Mesnage, Robin, Biserni, Martina, Balu, Sucharitha, Frainay, Clément, Poupin, Nathalie, Jourdan, Fabien, Wozniak, Eva, Xenakis, Theodoros, Mein, Charles A., Antoniou, Michael N.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2018
Matèries:
Molecular Toxicology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063328/
https://ncbi.nlm.nih.gov/pubmed/29947894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-018-2235-7
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