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miR-145 and miR-497 suppress TGF-β-induced epithelial–mesenchymal transition of non-small cell lung cancer by targeting MTDH

BACKGROUND: MicroRNAs (miRNAs) have been reported to play crucial roles in multiple cancers including non-small cell lung cancer (NSCLC). Here, we investigated the role of miR-145 and miR-497 in TGF-β-induced epithelial–mesenchymal transition (EMT) process of NSCLC. METHODS: We performed quantitativ...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Yin, Qi, Han, Yang, Zhu, Dongyi, Li, Zhanxia, Shan, Shan, Jin, Wenjing, Lu, Qingchun, Ren, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062944/
https://ncbi.nlm.nih.gov/pubmed/30065618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0601-4
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