Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates

Detection of acute HIV infection is critical for HIV public health and diagnostics. Clinical fourth-generation antigen (Ag)/antibody (Ab) combination (combo) and p24 Ag immunoassays have enhanced detection of acute infection compared to Ab-alone assays but require ongoing evaluation with currently c...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: Stone, Mars, Bainbridge, John, Sanchez, Ana M., Keating, Sheila M., Pappas, Andrea, Rountree, Wes, Todd, Chris, Bakkour, Sonia, Manak, Mark, Peel, Sheila A., Coombs, Robert W., Ramos, Eric M., Shriver, M. Kathleen, Contestable, Paul, Nair, Sangeetha Vijaysri, Wilson, David H., Stengelin, Martin, Murphy, Gary, Hewlett, Indira, Denny, Thomas N., Busch, Michael P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Immunoassays
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062817/
https://ncbi.nlm.nih.gov/pubmed/29793968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02045-17
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