PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart

Cardiac hypertrophy occurs in response to increased hemodynamic demand and can progress to heart failure. Identifying the key regulators of this process is clinically important. Though it is thought that the phosphorylation of histone deacetylase (HDAC) 2 plays a crucial role in the development of p...

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Vydáno v:Exp Mol Med
Hlavní autoři: Yoon, Somy, Kook, Taewon, Min, Hyun-Ki, Kwon, Duk-Hwa, Cho, Young Kuk, Kim, Mira, Shin, Sera, Joung, Hosouk, Jeong, Seung Hoon, Lee, Sumin, Kang, Gaeun, Park, Yunchul, Kim, Yong Sook, Ahn, Youngkeun, McMullen, Julie R., Gergs, Ulrich, Neumann, Joachim, Kim, Kyung Keun, Kim, Jungchul, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun, Eom, Gwang Hyeon
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062565/
https://ncbi.nlm.nih.gov/pubmed/30050113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0121-2
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