PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart

Cardiac hypertrophy occurs in response to increased hemodynamic demand and can progress to heart failure. Identifying the key regulators of this process is clinically important. Though it is thought that the phosphorylation of histone deacetylase (HDAC) 2 plays a crucial role in the development of p...

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發表在:Exp Mol Med
Main Authors: Yoon, Somy, Kook, Taewon, Min, Hyun-Ki, Kwon, Duk-Hwa, Cho, Young Kuk, Kim, Mira, Shin, Sera, Joung, Hosouk, Jeong, Seung Hoon, Lee, Sumin, Kang, Gaeun, Park, Yunchul, Kim, Yong Sook, Ahn, Youngkeun, McMullen, Julie R., Gergs, Ulrich, Neumann, Joachim, Kim, Kyung Keun, Kim, Jungchul, Nam, Kwang-Il, Kim, Young-Kook, Kook, Hyun, Eom, Gwang Hyeon
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062565/
https://ncbi.nlm.nih.gov/pubmed/30050113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0121-2
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