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Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a glycans

We have previously reported clinical data to suggest that colonization factor I (CFA/I) fimbriae of enterotoxigenic Escherichia coli (ETEC) can bind to Lewis a (Le(a)), a glycan epitope ubiquitous in the small intestinal mucosa of young children (<2 years of age), and individuals with a genetic m...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Mottram, Lynda, Liu, Jining, Chavan, Sonali, Tobias, Joshua, Svennerholm, Ann-Mari, Holgersson, Jan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062558/
https://ncbi.nlm.nih.gov/pubmed/30050155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29258-0
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