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Differentiating positional isomers of nucleoside modifications by higher-energy collisional dissociation mass spectrometry (HCD MS)

The analytical identification of positional isomers (e.g., 3-, N(4)-, 5-methylcytidine) within the >160 different post-transcriptional modifications found in RNA can be challenging. Conventional liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) approaches rely on chromatograp...

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Podrobná bibliografie
Vydáno v:J Am Soc Mass Spectrom
Hlavní autoři: Jora, Manasses, Burns, Andrew P., Ross, Robert L., Lobue, Peter A., Zhao, Ruoxia, Palumbo, Cody M., Beal, Peter A., Addepalli, Balasubrahmanyam, Limbach, Patrick A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062210/
https://ncbi.nlm.nih.gov/pubmed/29949056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1999-6
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