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Differentiating positional isomers of nucleoside modifications by higher-energy collisional dissociation mass spectrometry (HCD MS)
The analytical identification of positional isomers (e.g., 3-, N(4)-, 5-methylcytidine) within the >160 different post-transcriptional modifications found in RNA can be challenging. Conventional liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) approaches rely on chromatograp...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Am Soc Mass Spectrom |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6062210/ https://ncbi.nlm.nih.gov/pubmed/29949056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1999-6 |
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