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A comparison of toxicity and toxicokinetics in rats and dogs following twenty-eight-day, repeat-dose oral administration of nifurtimox

Nifurtimox has been an important treatment for trypanosomiasis for many years, but new research indicates that the drug may also be an effective therapy for malignant neuroblastoma. However, there have been few published reports evaluating the toxicity of nifurtimox in different species. Therefore,...

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Res (Camb)
Hauptverfasser: Li, Ye, Liu, Tian-tian, Jin, Hong-tao, Zhang, Piao-piao, Qin, Dan, Zhang, Qian-qian, Wu, Wen-tao, Yang, Cui-ping, Wang, Ai-ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062185/
https://ncbi.nlm.nih.gov/pubmed/30090523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00061h
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