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Identification of the Al-binding proteins that account for aluminum neurotoxicity and transport in vivo

Studies have shown that aluminum (Al) is the most abundant neurotoxic element on Earth, and is implicated in the pathogenesis of Alzheimer's disease (AD). However, the mechanisms underlying Al-induced neurotoxicity are still largely elusive. Based on affinity analyses with Al and LC-LTQ-MS, we...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Cheng, Dai, Wang, Xiaomei, Xi, Yu, Cao, Jiankang, Jiang, Weibo
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062109/
https://ncbi.nlm.nih.gov/pubmed/30090569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00261k
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