Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward

The gut-to-brain axis exhibits significant control over motivated behavior. However, mechanisms supporting this communication are poorly understood. We reveal that a gut-based bariatric surgery chronically elevates systemic bile acids and attenuates cocaine-induced elevations in accumbal dopamine. N...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Reddy, India A., Smith, Nicholas K., Erreger, Kevin, Ghose, Dipanwita, Saunders, Christine, Foster, Daniel J., Turner, Brandon, Poe, Amanda, Albaugh, Vance L., McGuinness, Owen, Hackett, Troy A., Grueter, Brad A., Abumrad, Naji N., Flynn, Charles Robb, Galli, Aurelio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061973/
https://ncbi.nlm.nih.gov/pubmed/30048457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006682
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