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A functional type II-A CRISPR–Cas system from Listeria enables efficient genome editing of large non-integrating bacteriophage

CRISPR–Cas systems provide bacteria with adaptive immunity against invading DNA elements including bacteriophages and plasmids. While CRISPR technology has revolutionized eukaryotic genome engineering, its application to prokaryotes and their viruses remains less well established. Here we report the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Hupfeld, Mario, Trasanidou, Despoina, Ramazzini, Livia, Klumpp, Jochen, Loessner, Martin J, Kilcher, Samuel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061871/
https://ncbi.nlm.nih.gov/pubmed/30053228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky544
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