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A functional type II-A CRISPR–Cas system from Listeria enables efficient genome editing of large non-integrating bacteriophage

CRISPR–Cas systems provide bacteria with adaptive immunity against invading DNA elements including bacteriophages and plasmids. While CRISPR technology has revolutionized eukaryotic genome engineering, its application to prokaryotes and their viruses remains less well established. Here we report the...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Hupfeld, Mario, Trasanidou, Despoina, Ramazzini, Livia, Klumpp, Jochen, Loessner, Martin J, Kilcher, Samuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061871/
https://ncbi.nlm.nih.gov/pubmed/30053228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky544
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