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High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing
DNA polymerase fidelity is affected by both intrinsic properties and environmental conditions. Current strategies for measuring DNA polymerase error rate in vitro are constrained by low error subtype sensitivity, poor scalability, and lack of flexibility in types of sequence contexts that can be tes...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061839/ https://ncbi.nlm.nih.gov/pubmed/29718339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky296 |
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