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The histamine H(3) receptor inverse agonist pitolisant reduces body weight in obese mice

The pharmacological profile of pitolisant, a histamine H(3) receptor antagonist/inverse agonist, indicates that this compound might reduce body weight and metabolic disturbances. Therefore, we studied the influence of pitolisant on body weight, water and sucrose intake as well as metabolic disturban...

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Detalhes bibliográficos
Publicado no:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Kotańska, Magdalena, Kuder, Kamil J., Szczepańska, Katarzyna, Sapa, Jacek, Kieć-Kononowicz, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061715/
https://ncbi.nlm.nih.gov/pubmed/29802412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-018-1516-2
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