Melanoma Brain Metastases: Local Therapies, Targeted Therapies, Immune Checkpoint Inhibitors and Their Combinations—Chances and Challenges

Recent phase II trials have shown that BRAF/MEK inhibitors and immune checkpoint inhibitors are active in patients with melanoma brain metastases (MBM), reporting intracranial disease control rates of 50–75%. Furthermore, retrospective analyses suggest that combining stereotactic radiosurgery with i...

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Bibliografiske detaljer
Udgivet i:Am J Clin Dermatol
Main Authors: Kuske, Marvin, Rauschenberg, Ricarda, Garzarolli, Marlene, Meredyth-Stewart, Michelle, Beissert, Stefan, Troost, Esther G. C., Glitza, Oliva Isabella Claudia, Meier, Friedegund
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061393/
https://ncbi.nlm.nih.gov/pubmed/29417399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40257-018-0346-9
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