Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer’s disease

Alzheimer’s disease (AD) is a common neurological disease that causes dementia in humans. Although the reports of associated pathological genes have been increasing, the molecular mechanism leading to the accumulation of amyloid-β (Aβ) in human brain is still not well understood. To identify novel g...

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Bibliographische Detailangaben
Veröffentlicht in:Hum Genet
Hauptverfasser: Yamaguchi-Kabata, Yumi, Morihara, Takashi, Ohara, Tomoyuki, Ninomiya, Toshiharu, Takahashi, Atsushi, Akatsu, Hiroyasu, Hashizume, Yoshio, Hayashi, Noriyuki, Shigemizu, Daichi, Boroevich, Keith A., Ikeda, Manabu, Kubo, Michiaki, Takeda, Masatoshi, Tsunoda, Tatsuhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2018
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061045/
https://ncbi.nlm.nih.gov/pubmed/30006735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-018-1906-z
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