Combining SGLT2 Inhibition With a Thiazolidinedione Additively Attenuate the Very Early Phase of Diabetic Nephropathy Progression in Type 2 Diabetes Mellitus

Although both sodium glucose co-transporter 2 inhibition by dapagliflozin and thiazolidinedione, pioglitazone have glucose-lowering and anti-inflammatory effects, the therapeutic efficacy of their combination on diabetic nephropathy has not been investigated. 9-week-old male db/db mice were randomly...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Han, Eugene, Shin, Eugene, Kim, Gyuri, Lee, Ji-Yeon, Lee, Yong-ho, Lee, Byung-Wan, Kang, Eun Seok, Cha, Bong-Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060671/
https://ncbi.nlm.nih.gov/pubmed/30072956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00412
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