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Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors

BACKGROUND: Small intestinal neuroendocrine tumors (SI-NETs) originate from enterochromaffin cells scattered in the intestinal mucosa of the ileum and jejunum. Loss of one copy of chromosome 18 is the most frequent observed aberration in primary tumors and metastases. The aim of this study was to in...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Barazeghi, Elham, Prabhawa, Surendra, Norlén, Olov, Hellman, Per, Stålberg, Peter, Westin, Gunnar
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060499/
https://ncbi.nlm.nih.gov/pubmed/30045709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4579-z
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