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Global Stabilization of Boolean Networks to Control the Heterogeneity of Cellular Responses

Boolean networks (BNs) have been widely used as a useful model for molecular regulatory networks in systems biology. In the state space of BNs, attractors represent particular cell phenotypes. For targeted therapy of cancer, there is a pressing need to control the heterogeneity of cellular responses...

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Pubblicato in:Front Physiol
Autori principali: Yang, Jung-Min, Lee, Chun-Kyung, Cho, Kwang-Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060448/
https://ncbi.nlm.nih.gov/pubmed/30072906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00774
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