Polymeric Immunoglobulin Receptor Mediates Immune Excretion of Mucosal IgM–Antigen Complexes Across Intestinal Epithelium in Flounder (Paralichthys olivaceus)

Polymeric immunoglobulin receptor (pIgR) is one important player of mucosal defenses, but very little is known on pIgR-mediated immune excretion of the antigens that penetrate mucosal surface in fish. Previously, we cloned the pIgR of flounder (Paralichthys olivaceus) and developed anti-pIgR antibod...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Sheng, Xiuzhen, Qian, Xiaoyu, Tang, Xiaoqian, Xing, Jing, Zhan, Wenbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060246/
https://ncbi.nlm.nih.gov/pubmed/30072985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01562
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