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Pontin/Tip49 negatively regulates JNK-mediated cell death in Drosophila

Pontin (Pont), also known as Tip49, encodes a member of the AAA+ (ATPases Associated with Diverse Cellular Activities) superfamily and plays pivotal roles in cell proliferation and growth, yet its function in cell death has remained poorly understood. Here we performed a genetic screen for dominant...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Wang, Xingjun, Huang, Xirui, Wu, Chenxi, Xue, Lei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060144/
https://ncbi.nlm.nih.gov/pubmed/30062057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0074-1
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