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Targeting sphingolipid metabolism as an approach for combination therapies in haematological malignancies

Conventional chemotherapy-based drug combinations have, until recently, been the backbone of most therapeutic strategies for cancer. In a time of emerging rationale drug development, targeted therapies are beginning to be added to traditional chemotherapeutics to synergistically enhance clinical res...

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Publicado en:Cell Death Discov
Main Authors: Lewis, Alexander C., Wallington-Beddoe, Craig T., Powell, Jason A., Pitson, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060109/
https://ncbi.nlm.nih.gov/pubmed/30062053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0075-0
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