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Therapeutic targets and emerging treatment options in gastrointestinal acute graft-versus-host disease

INTRODUCTION: Graft-versus-host disease (GVHD) continues to be the major lethal complication of allogeneic hematopoietic stem cell transplantation (HCT) but the standard of care, high dose steroids, has not changed in 40 years. Approximately 50% of GVHD patients will develop steroid refractory disea...

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Publicat a:Expert Opin Orphan Drugs
Autors principals: Renteria, Anne S., Levine, John E., Ferrara, James L. M.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059654/
https://ncbi.nlm.nih.gov/pubmed/30057862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/21678707.2016.1166949
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