Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer

BACKGROUND: Exposure to ionizing radiation during childhood is a well-established risk factor for thyroid cancer. However, the genetic mechanisms of radiation-associated carcinogenesis remain not fully understood. METHODS: In this study, we used targeted next-generation sequencing and RNA-Seq to stu...

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Bibliografske podrobnosti
izdano v:J Natl Cancer Inst
Main Authors: Efanov, Alexey A, Brenner, Alina V, Bogdanova, Tetiana I, Kelly, Lindsey M, Liu, Pengyuan, Little, Mark P, Wald, Abigail I, Hatch, Maureen, Zurnadzy, Liudmyla Y, Nikiforova, Marina N, Drozdovitch, Vladimir, Leeman-Neill, Rebecca, Mabuchi, Kiyohiko, Tronko, Mykola D, Chanock, Stephen J, Nikiforov, Yuri E
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059206/
https://ncbi.nlm.nih.gov/pubmed/29165687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx209
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