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Aggravated Atherosclerosis and Vascular Inflammation With Reduced Kidney Function Depend on Interleukin-17 Receptor A and Are Normalized by Inhibition of Interleukin-17A

Effective therapy of atherosclerotic complications in patients with chronic kidney disease (CKD) is an unmet clinical need. Cardiovascular events are the most common cause of death. At a glomerular filtration rate ≤60 ml/min, these events are increased also after correction for common risk factors....

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Publicat a:JACC Basic Transl Sci
Autors principals: Nordlohne, Johannes, Helmke, Alexandra, Ge, Shuwang, Rong, Song, Chen, Rongjun, Waisman, Ari, Haller, Hermann, von Vietinghoff, Sibylle
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058956/
https://ncbi.nlm.nih.gov/pubmed/30062194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2017.08.005
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