DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status

Alteration in the DNA replication, repair or recombination processes is a highly relevant mechanism of genomic instability. Despite genomic aberrations manifested in hematologic malignancies, such a defect as a source of biomarkers has been underexplored. Here, we investigated the prognostic value o...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Grgurevic, Srdana, Montilla-Perez, Patricia, Bradbury, Alice, Gilhodes, Julia, Queille, Sophie, Pelofy, Sandrine, Bancaud, Aurélien, Filleron, Thomas, Ysebaert, Loïc, Récher, Christian, Laurent, Guy, Fournié, Jean-Jacques, Cazaux, Christophe, Quillet-Mary, Anne, Hoffmann, Jean-Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058778/
https://ncbi.nlm.nih.gov/pubmed/29567785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.174243
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