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Liver-targeted delivery of insulin-loaded nanoparticles via enterohepatic circulation of bile acids

Liver is the primary acting site of insulin. In this study, we developed innovative nanoparticles for oral and liver-targeted delivery of insulin by using enterohepatic circulation of bile acids. The nanoparticles were produced from cholic acid and quaternary ammonium modified chitosan derivative an...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Zhang, Zhe, Li, Hongxiang, Xu, Guangrui, Yao, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058709/
https://ncbi.nlm.nih.gov/pubmed/29791242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1469685
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