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Development of novel bioadhesive granisetron hydrochloride spanlastic gel and insert for brain targeting and study their effects on rats

The aim of this study was to formulate granisetron hydrochloride (GH) spanlastic in mucoadhesive gels and lyophilized inserts for intranasal administration to improve GH bioavailability and brain targeting. Carpapol 934 and HPMC were incorporated in GH spanlastic in nasal gels (GHSpNGs). Gelatin and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Drug Deliv
Päätekijät: Abdelmonem, Rehab, el Nabarawi, Mohamed, Attia, Alshaimaa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058699/
https://ncbi.nlm.nih.gov/pubmed/29228824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1413447
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