Pulmonary delivery of influenza vaccine formulations in cotton rats: site of deposition plays a minor role in the protective efficacy against clinical isolate of H1N1pdm virus

Administration of influenza vaccines to the lungs could be an attractive alternative to conventional parenteral administration. In this study, we investigated the deposition site of pulmonary delivered liquid and powder influenza vaccine formulations and its relation to their immunogenicity and prot...

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Bibliografiske detaljer
Udgivet i:Drug Deliv
Main Authors: Bhide, Yoshita, Tomar, Jasmine, Dong, Wei, de Vries-Idema, Jacqueline, Frijlink, Henderik W., Huckriede, Anke, Hinrichs, Wouter L. J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058687/
https://ncbi.nlm.nih.gov/pubmed/29451040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1435748
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