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Formulation and in vivo assessment of terconazole-loaded polymeric mixed micelles enriched with Cremophor EL as dual functioning mediator for augmenting physical stability and skin delivery

The aim of the current study was to formulate terconazole (TCZ) loaded polymeric mixed micelles (PMMs) incorporating Cremophor EL as a stabilizer and a penetration enhancer. A 2(3) full factorial design was performed using Design-Expert® software for the optimization of the PMMs which were formulate...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Abd-Elsalam, Wessam H., El-Zahaby, Sally A., Al-Mahallawi, Abdulaziz M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058577/
https://ncbi.nlm.nih.gov/pubmed/29411650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1436098
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