Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells

BACKGROUND: Glioblastoma (GBM) is a primary brain tumor with a 5-year survival rate of ≤5%. We have shown earlier that GBM-antibody-linked curcumin (CC) and also phytosomal curcumin (CCP) rescue 50–60% of GBM-bearing mice while repolarizing the tumor-associated microglia/macrophages (TAM) from the t...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Mukherjee, Sumit, Fried, Angela, Hussaini, Rahman, White, Richard, Baidoo, Juliet, Yalamanchi, Sri, Banerjee, Probal
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058381/
https://ncbi.nlm.nih.gov/pubmed/30041669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0792-5
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