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Hybrid Capture‐Based Comprehensive Genomic Profiling Identifies Lung Cancer Patients with Well‐Characterized Sensitizing Epidermal Growth Factor Receptor Point Mutations That Were Not Detected by Standard of Care Testing

BACKGROUND. In our recent study, of cases positive for epidermal growth factor receptor (EGFR) exon 19 deletions using comprehensive genomic profiling (CGP), 17/77 (22%) patients with prior standard of care (SOC) EGFR testing results available were previously negative for exon 19 deletion. Our aim w...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Suh, James H., Schrock, Alexa B., Johnson, Adrienne, Lipson, Doron, Gay, Laurie M., Ramkissoon, Shakti, Vergilio, Jo‐Anne, Elvin, Julia A., Shakir, Abdur, Ruehlman, Peter, Reckamp, Karen L., Ou, Sai‐Hong Ignatius, Ross, Jeffrey S., Stephens, Philip J., Miller, Vincent A., Ali, Siraj M.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058345/
https://ncbi.nlm.nih.gov/pubmed/29540602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0493
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